:root{--ink:#182428;--muted:#667075;--line:#dce1df;--paper:#fff;--blue:#087f78;--pale:#edf7f5;--radius:4px}*{box-sizing:border-box}body{margin:0;background:var(--paper);color:var(--ink);font:16px/1.6 'DM Sans',system-ui,sans-serif}a{color:inherit;text-decoration:none}a:hover{text-decoration:underline}button,input,textarea,select{font:inherit}button,a,input,textarea,select{outline-offset:4px}button{cursor:pointer}button:disabled{cursor:not-allowed;opacity:.5}h1,h2,h3,p{margin:0}h1,h2,h3{font-family:Manrope,system-ui,sans-serif;line-height:1.18;letter-spacing:-.035em}h1{font-size:clamp(2.3rem,4vw,3.65rem);font-weight:800}h2{font-size:1.8rem}h3{font-size:1.2rem}.site{max-width:1376px;margin:auto;padding:0 56px}.topline{display:flex;justify-content:space-between;border-bottom:1px solid var(--line);padding:13px 0;font-size:12px;letter-spacing:.09em}.topline span:first-child{font-weight:700}header{display:flex;align-items:center;padding:27px 0 25px;gap:28px}.wordmark{font-family:Manrope,system-ui,sans-serif;font-weight:800;font-size:62px;letter-spacing:-.085em;line-height:1}.wordmark span{display:inline-block;width:.169em;height:.169em;margin-left:.045em;border-radius:50%;background:var(--blue);color:transparent;overflow:hidden;vertical-align:.022em;letter-spacing:0}.wordmark:hover{text-decoration:none}.brand-note{border-left:1px solid var(--line);padding-left:25px;line-height:1.35;font-size:14px;color:var(--muted)}.studio-link{margin-left:auto;font-size:14px;font-weight:600;border-bottom:1px solid var(--ink)}nav{display:flex;gap:34px;border-top:2px solid var(--ink);border-bottom:1px solid var(--line);padding:17px 0;font-weight:700;font-size:15px}nav a:first-child{color:var(--blue)}main{padding:40px 0 70px;min-height:55vh}.section-heading{display:flex;align-items:end;justify-content:space-between;margin-bottom:28px;gap:20px}.section-heading h1{margin-top:10px}.section-heading>p{color:var(--muted);padding-bottom:5px;font-size:15px}.eyebrow{display:block;font-size:12px;font-weight:800;letter-spacing:.1em;text-transform:uppercase;color:var(--blue)}.lead-grid{display:grid;grid-template-columns:1.7fr 1fr;gap:36px}.lead .card-image{height:360px}.card-image{height:235px;display:block;overflow:hidden;background:#e9edee}.card-image img{width:100%;height:100%;object-fit:cover;transition:transform .3s}.card-image:hover img{transform:scale(1.025)}.card-copy{padding:21px 0}.card-copy h2{margin:9px 0 13px}.lead .card-copy h2{font-size:clamp(1.9rem,3vw,2.65rem)}.card-copy p{color:var(--muted);max-width:650px;font-size:16px;line-height:1.65}.meta{font-size:12px;color:var(--muted);margin-top:15px}.side-stack{border-left:1px solid var(--line);padding-left:32px}.aside-heading{font-size:12px;font-weight:700;letter-spacing:.15em;border-bottom:2px solid var(--ink);padding-bottom:14px}.side-story{display:block;border-bottom:1px solid var(--line);padding:24px 0}.side-story h2{font-size:1.55rem;margin:10px 0}.side-story .meta{display:block}.section-rule{display:flex;justify-content:space-between;align-items:center;border-top:2px solid var(--ink);padding-top:21px;margin:40px 0 28px}.section-rule h2{font-size:1.8rem}.section-rule>span{font-size:12px;letter-spacing:.12em;color:var(--muted)}.feed-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:28px}.feed-grid h2{font-size:1.4rem}.type-art{height:100%;min-height:230px;padding:30px;display:flex;flex-direction:column;justify-content:space-between;overflow:hidden}.type-art>span{font-family:Manrope,system-ui,sans-serif;font-weight:800;font-size:clamp(2rem,4vw,4rem);line-height:1.05;letter-spacing:-.05em}.type-art small{font-size:11px;letter-spacing:.13em;margin-top:30px}.blue{background:#224cf0;color:white}.lime{background:#d5ef82;color:#293918}.pink{background:#f2c6c2;color:#683930}.orange{background:#f7b46d;color:#583315}.launch{background:var(--pale);padding:65px;margin:30px 0}.launch h2{font-size:clamp(3rem,7vw,6rem);margin:20px 0}.launch p{max-width:480px;color:var(--muted)}footer{border-top:2px solid var(--ink);padding:40px 0 35px;display:flex;gap:24px;flex-wrap:wrap;align-items:center}footer .wordmark{font-size:38px}footer p{font-size:14px;color:var(--muted)}footer>div{margin-left:auto;display:flex;gap:22px;font-size:13px}footer small{width:100%;color:var(--muted);font-size:12px}.preview-banner{background:#fff3cf;color:#684915;padding:13px 20px;font-size:13px;margin-top:20px;border-left:3px solid #c99b2f}.story{max-width:900px;margin:auto}.story h1{font-size:clamp(2.5rem,5vw,4.5rem);margin:20px 0}.story .dek{font-size:21px;color:var(--muted);max-width:780px}.story>.meta{margin:25px 0}.story>img{width:100%;max-height:530px;object-fit:cover}.story>.type-art{min-height:350px}.back{display:block;font-size:14px;margin-bottom:25px;color:var(--muted)}.prose{max-width:680px;margin:40px auto;font-size:18px;line-height:1.8}.prose>p{margin:25px 0;white-space:normal}.prose a,.policy a{color:var(--blue);text-decoration:underline}.disclosure{padding:20px;background:var(--pale);font-size:14px}.product-links{margin-top:35px}.product-links a{display:inline-block;margin:10px 8px 0 0}.policy{max-width:760px;margin:auto}.policy h1{margin-bottom:32px}.policy p{margin-bottom:25px}.ad{border:1px solid var(--line);padding:25px;text-align:center;margin-top:30px;font-size:13px;color:var(--muted)}.ad>span{display:block;font-size:11px;letter-spacing:.2em}.ad button{margin:15px}.skip{position:absolute;left:-9999px}.skip:focus{left:16px;top:16px;z-index:99;background:white;padding:15px}.button,button{border:1px solid var(--blue);background:var(--blue);color:#fff;padding:11px 18px;border-radius:3px;font-size:14px;font-weight:700;line-height:1.3;text-decoration:none!important}.secondary{background:white;color:var(--ink);border-color:var(--line)}.danger{background:#fff;color:#a83232;border-color:#ebcccc}.text-button{background:none;color:var(--blue);border:0;padding:4px;font-size:14px}.button:hover,button:hover{filter:brightness(.97)}
/* Editorial workspace */
.studio-body{background:#f5f6f8}.studio-shell{display:grid;grid-template-columns:230px minmax(0,1fr);min-height:100vh}.sidebar{padding:35px 22px;background:#172428;color:#d4dcde}.sidebar .wordmark{color:white;font-size:43px}.sidebar .submark{display:block;font-size:11px;letter-spacing:.15em;margin-top:12px;color:#9aaeb3}.sidebar nav{display:flex;flex-direction:column;gap:7px;border:0;margin:45px 0 20px;padding:0}.sidebar nav button{text-align:left;padding:13px;background:none;color:#b5c4c7;border:0;font-weight:500;font-size:15px}.sidebar nav button.active{background:#2e4248;color:white}.sidebar a{font-size:14px;display:block;margin:22px 12px}.studio-main{padding:40px clamp(22px,4vw,65px);min-width:0}.studio-top{display:flex;align-items:center;justify-content:space-between;margin-bottom:30px;gap:15px}.studio-top h1{font-size:2.4rem}.studio-top p{color:var(--muted);margin-top:7px}.status-pill{font-size:12px;background:#e8edf6;padding:7px 10px;border-radius:20px;white-space:nowrap}.panel{background:white;border:1px solid var(--line);padding:26px;margin:20px 0;border-radius:4px}.panel h2{font-size:1.35rem;margin-bottom:10px}.panel p{color:var(--muted)}.notice{border-left:3px solid #d19f32;background:#fff7df;padding:18px 22px;font-size:14px;margin-bottom:20px}.stats{display:grid;grid-template-columns:repeat(4,minmax(0,1fr));gap:18px}.stat{background:white;border:1px solid var(--line);padding:22px}.stat span{display:block;font-size:13px;color:var(--muted)}.stat strong{font-size:35px;font-family:Manrope,sans-serif}.toolbar{display:flex;justify-content:space-between;align-items:center;gap:12px;margin:25px 0 15px}.toolbar h2{font-size:1.4rem}.row{display:flex;justify-content:space-between;align-items:center;gap:20px;border-top:1px solid var(--line);padding:19px 0}.row:first-of-type{border-top:0}.row h3{font-size:1.1rem;line-height:1.4;margin:5px 0}.row p{font-size:14px;color:var(--muted)}.row .actions{display:flex;gap:9px;flex-shrink:0;align-items:center}.badge{display:inline-block;font-size:11px;text-transform:uppercase;letter-spacing:.08em;padding:3px 7px;background:#eef2ff;color:#354a9b;margin-right:8px}.badge.published{background:#e8f2df;color:#486432}.empty{text-align:center;padding:48px 15px;color:var(--muted)}label{display:block;font-size:14px;font-weight:700;margin-bottom:7px}input,select,textarea{display:block;width:100%;border:1px solid #cdd4d8;background:#fff;padding:11px 13px;border-radius:3px;color:var(--ink);font-size:15px}textarea{resize:vertical;min-height:100px}.field{margin-bottom:22px}.field small{display:block;margin-top:7px;color:var(--muted);font-size:13px}.form-grid{display:grid;grid-template-columns:1fr 1fr;gap:0 22px}.check{display:flex;align-items:flex-start;gap:12px;font-weight:500}.check input{width:19px;height:19px;margin-top:3px;flex-shrink:0}.form-actions{display:flex;gap:12px;align-items:center;flex-wrap:wrap}.editor-body{min-height:360px;line-height:1.7}.auth-wrap{max-width:460px;margin:12vh auto;padding:0 22px}.auth-wrap .wordmark{font-size:52px}.auth-wrap h1{font-size:1.9rem;margin:30px 0 12px}.auth-wrap p{color:var(--muted);margin-bottom:25px}.error{background:#fff0ef;color:#982b21;border:1px solid #e9b6b1;padding:14px 18px;margin:15px 0;font-size:14px}.success{background:#e9f3e6;color:#365b2d;border:1px solid #c5d8bd;padding:14px 18px;margin:15px 0;font-size:14px}#toast:empty{display:none}#toast{position:sticky;top:10px;z-index:10}.editor-sidebar{color:var(--muted);font-size:14px;margin:15px 0}.mobile-studio-bar{display:none}code{font-size:13px;background:#f0f2f5;padding:2px 5px}.run-detail{font-size:13px;white-space:pre-wrap;overflow-wrap:anywhere}.deal-box{background:#f3f5f8;padding:26px;border-top:3px solid var(--blue);margin-top:25px}.deal-box h2{font-size:1.5rem;margin:7px 0 12px}.deal-box p{color:var(--muted);font-size:15px}.deal-box a{display:inline-block;margin-top:16px;color:var(--blue);font-weight:700;font-size:14px}
@media(max-width:1000px){.site{padding:0 30px}.lead-grid{grid-template-columns:1.4fr 1fr;gap:24px}.side-stack{padding-left:23px}.lead .card-image{height:290px}.feed-grid{gap:22px}.card-image{height:200px}.studio-shell{grid-template-columns:190px 1fr}.studio-main{padding:30px 24px}.row{align-items:flex-start}.row .actions{flex-direction:column}.section-heading>p{max-width:190px}.form-grid{grid-template-columns:1fr}.stats{gap:10px;grid-template-columns:repeat(2,minmax(0,1fr))}.stat{padding:16px}}
@media(max-width:700px){.site{padding:0 20px}.topline span:last-child{display:none}header{padding:24px 0;gap:16px;flex-wrap:wrap}.brand-note{padding-left:16px;font-size:13px}.wordmark{font-size:49px}nav{gap:23px;overflow-x:auto;white-space:nowrap;font-size:14px;padding:14px 0}.studio-link{font-size:13px}.section-heading{display:block}.section-heading>p{max-width:none;margin-top:12px}.section-heading h1{font-size:2.35rem}.eyebrow{font-size:11px}main{padding-top:28px}.lead-grid{grid-template-columns:1fr}.lead .card-image{height:270px}.side-stack{border-left:0;padding-left:0}.side-story h2{font-size:1.4rem}.feed-grid{grid-template-columns:1fr}.feed-grid .card{display:grid;grid-template-columns:115px 1fr;gap:16px;border-bottom:1px solid var(--line);padding-bottom:20px}.feed-grid .card-image{height:135px}.feed-grid .card-copy{padding:0}.feed-grid .card-copy h2{font-size:1.2rem}.feed-grid .card-copy p{display:none}.feed-grid .type-art{min-height:135px;padding:12px}.feed-grid .type-art span{font-size:1.6rem}.feed-grid .type-art small{display:none}.section-rule>span{display:none}.launch{padding:30px}.launch h2{font-size:3.4rem}footer>div{width:100%;margin:0;flex-wrap:wrap;gap:16px}footer p{width:100%}.story h1{font-size:2.5rem}.story .dek{font-size:18px}.prose{font-size:17px}.studio-shell{display:block}.sidebar{padding:18px 20px}.sidebar .wordmark{font-size:32px}.sidebar .submark{display:none}.sidebar nav{flex-direction:row;overflow:auto;margin:20px 0 0;gap:5px}.sidebar nav button{white-space:nowrap;font-size:13px;padding:10px}.sidebar>a{display:inline-block;margin:15px 15px 0 0}.studio-main{padding:24px 18px}.studio-top{display:block}.studio-top h1{font-size:2rem}.status-pill{display:inline-block;margin-top:15px}.stats{grid-template-columns:repeat(2,minmax(0,1fr))}.stat{padding:12px}.stat strong{font-size:28px}.stat span{font-size:12px}.panel{padding:20px}.row{display:block}.row .actions{flex-direction:row;margin-top:14px;flex-wrap:wrap}.toolbar{align-items:flex-start}.form-actions button{flex:1}.section-heading{margin-bottom:22px}}
.card-image img{object-position:center 20%}

.stat small{display:block;color:var(--muted);font-size:12px;line-height:1.5;margin-top:8px}

.article-visual{margin:24px 0}.article-visual img{display:block;width:100%;height:auto;border-radius:4px}.article-visual figcaption,.article-graphic figcaption{font-size:12px;color:var(--muted);margin-top:8px}.card-image .article-visual{margin:0;width:100%;height:100%}.card-image .article-visual img{height:100%;object-fit:cover}.card-image figcaption{display:none}.media-panel{border-top:1px solid var(--line);padding:24px 0;margin:24px 0}.media-panel p{margin:12px 0}.media-grid{display:grid;grid-template-columns:repeat(auto-fit,minmax(220px,1fr));gap:20px;margin:20px 0}.media-grid img{width:100%;height:auto}.article-graphic{background:#f1f4f5;border-radius:6px;padding:24px;margin:28px 0}.graphic-item{margin:20px 0}.graphic-item p{font-size:14px}.chart-bar{height:20px;background:#354a9b;margin:8px 0;min-width:0}

.media-grid{grid-template-columns:repeat(auto-fit,minmax(min(220px,100%),1fr))}.media-card{min-width:0;border:1px solid var(--line);border-radius:6px;padding:16px}.media-card img{display:block;border-radius:4px}.media-placeholder{aspect-ratio:3/2;min-height:160px;background:#f1f4f8;border:1px dashed #b6c2d2;border-radius:4px;display:flex;flex-direction:column;justify-content:center;align-items:center;text-align:center;padding:20px;color:var(--muted)}.media-placeholder>span{font-size:36px}.media-placeholder p{font-size:14px}.media-status{padding:12px 16px;background:var(--pale);border-radius:4px}.media-update-error{color:#982b21!important}

/* Editorial articles and composable reading aids. */
.story-editorial{max-width:1140px}.story-editorial>h1,.story-editorial>.dek{max-width:900px}.key-takeaways{background:#edf3ef;border:1px solid #d4e1d7;border-left:5px solid #315a47;border-radius:6px;padding:26px 30px;margin:28px 0 32px}.key-takeaways h2{font-size:1.45rem;margin:8px 0 16px}.key-takeaways .eyebrow{color:#315a47}.key-takeaways ul{padding-left:22px;margin:0;display:grid;gap:12px;max-width:900px}.key-takeaways li{padding-left:5px;font-size:17px;line-height:1.65}.story-layout{margin:40px auto;max-width:740px}.story-layout.has-support{display:grid;grid-template-columns:minmax(0,1fr) minmax(240px,300px);gap:48px;max-width:none;align-items:start}.story-layout>.prose{grid-column:1;grid-row:1;margin:0;min-width:0;max-width:740px}.support-panel{grid-column:2;grid-row:1;background:#f7f4eb;border:1px solid #e3dcc7;border-top:4px solid #897343;border-radius:5px;padding:24px;min-width:0}.support-panel h2{font-size:1.4rem;margin:9px 0 20px}.support-panel .eyebrow{color:#786136}.support-panel ul{list-style:none;padding:0;margin:0;display:grid;gap:0}.support-panel li{padding:13px 0;border-bottom:1px solid #e3dcc7;font-size:15px;line-height:1.6;overflow-wrap:anywhere}.support-panel li:last-child{border-bottom:0}.support-panel label{display:flex;gap:10px;font-size:15px;font-weight:400;line-height:1.6;margin:0;cursor:pointer}.support-panel input{width:17px;height:17px;flex:0 0 17px;margin-top:4px;accent-color:#315a47}.support-panel input:checked+span{text-decoration:line-through;color:#667075}.support-note{font-size:13px;margin:15px 0 0;color:var(--muted)}.prose h2,.rich-editor h2{font-size:1.8rem;line-height:1.3;margin:35px 0 16px}.prose h3,.rich-editor h3{font-size:1.3rem;line-height:1.4;margin:28px 0 12px}.prose ul,.prose ol{padding-left:27px;margin:24px 0}.prose li{padding-left:5px;margin:10px 0}.prose blockquote,.rich-editor blockquote{border-left:4px solid #224cf0;background:#eef2ff;padding:20px 24px;margin:28px 0;font-size:1.05em}.prose blockquote p{margin:0 0 12px}.prose{overflow-wrap:anywhere}.rich-toolbar{display:flex;gap:6px;flex-wrap:wrap;background:#f5f6f8;border:1px solid #cdd4d8;border-bottom:0;padding:10px;border-radius:4px 4px 0 0}.rich-toolbar button{padding:8px 10px;font-size:13px}.rich-editor{border:1px solid #cdd4d8;border-radius:0 0 4px 4px;padding:22px;background:#fff;overflow-wrap:anywhere;line-height:1.8;font-size:17px;min-height:360px}.rich-editor p{margin:0 0 18px}.rich-editor a{color:var(--blue);text-decoration:underline}.rich-editor:focus{outline:2px solid #224cf0;outline-offset:2px}.support-editor{border:1px solid var(--line);border-radius:4px;margin:28px 0;padding:22px;min-width:0}.support-editor legend{font-weight:700;padding:0 8px}.support-editor>p{margin:0 0 20px}.layout-preview{margin:24px 0}.layout-preview summary{cursor:pointer;color:var(--blue);font-weight:700}.layout-preview .support-panel{max-width:400px}.article-compose [hidden]{display:none}.article-compose small{line-height:1.6}.article-compose textarea{min-height:80px}.story-editorial>.article-visual img{max-height:620px;object-fit:cover}.story-editorial .prose>.article-visual{margin:36px 0}
@media(max-width:900px){.story-layout.has-support{display:flex;flex-direction:column;gap:28px}.story-layout>.support-panel{width:100%}.story-layout>.prose{max-width:none;width:100%}.key-takeaways{padding:22px}.key-takeaways li{font-size:16px}.support-panel{padding:22px}.rich-editor{padding:16px}.support-editor{padding:16px}.rich-toolbar{gap:5px;padding:8px}}
.story-editorial>img{object-position:center 20%}
.article-share{margin:24px 0 32px;padding:20px 0;border-top:1px solid var(--line);border-bottom:1px solid var(--line)}.share-label{display:block;font-size:12px;font-weight:700;letter-spacing:.08em;text-transform:uppercase;margin-bottom:12px}.share-actions{display:flex;gap:8px;flex-wrap:wrap}.share-action{display:inline-flex;align-items:center;justify-content:center;min-height:44px;padding:8px 15px;border:1px solid var(--line);border-radius:4px;background:white;color:var(--ink);font:600 14px/1.4 'DM Sans',system-ui,sans-serif;text-decoration:none}.share-action:hover{background:var(--pale);border-color:var(--blue);text-decoration:none}.article-share [hidden]{display:none}.share-status:empty{display:none}.share-status,.instagram-help,.share-copy-fallback{margin-top:12px;font-size:14px;color:var(--muted)}.instagram-help p{margin-bottom:8px}.instagram-help a{color:var(--blue);text-decoration:underline}.share-copy-fallback label{display:block}.share-copy-fallback textarea{display:block;width:100%;margin-top:8px;padding:10px;border:1px solid var(--line);color:var(--ink);background:white;resize:vertical}

.header-social{display:flex;align-items:center;gap:8px;margin-left:auto;flex-shrink:0}.header-social a{display:inline-flex;align-items:center;justify-content:center;width:44px;height:44px;border:1px solid var(--line);border-radius:50%;color:var(--ink);transition:color .15s,background .15s,border-color .15s}.header-social a:hover{color:var(--blue);background:var(--pale);border-color:var(--blue);text-decoration:none}.header-social a:focus-visible{outline:2px solid var(--blue)}.header-social svg{width:20px;height:20px;display:block}@media(max-width:700px){.header-social{gap:6px}.header-social a{width:44px;height:44px}header .brand-note{flex:1;min-width:115px}}


.share-action{gap:8px}.share-icon{display:block;width:18px;height:18px;flex:0 0 18px}

/* NeoMD's medical research identity */
.wordmark .md{display:inline;width:auto;height:auto;background:none;color:var(--blue);margin:0;vertical-align:baseline;letter-spacing:-.055em;border-radius:0;overflow:visible}.header-label{margin-left:auto;font-size:11px;letter-spacing:.14em;color:var(--muted)}.blue{background:#064e50}.lime{background:#d5eadc}.pink{background:#e2dff0;color:#39315a}.orange{background:#f1e6ce;color:#55452c}.site>nav{gap:25px;font-size:14px}.launch{background:linear-gradient(120deg,#edf7f5,#f5f3e9);border-left:5px solid #087f78}.evidence-panel{background:#edf7f5;border:1px solid #c3dfd9;padding:24px;margin:25px 0}.evidence-panel h2{font-size:1.4rem;margin:8px 0 16px}.evidence-panel p{margin:12px 0;white-space:pre-line}.evidence-panel a{color:var(--blue);text-decoration:underline}.medical-note{font-size:13px;color:var(--muted);border-left:3px solid var(--blue);padding:10px 16px;margin:20px 0}.medical-editor{border-top:2px solid var(--blue);padding-top:24px;margin:24px 0}.medical-editor>p{margin:12px 0 20px}@media(max-width:700px){.header-label{display:none}.topline span:last-child{display:none}.site>nav{overflow:auto;white-space:nowrap}.evidence-panel{padding:18px}}